Laguna Hills / South Orange County

Medical Retail Space in Laguna Hills

Medical-retail in Laguna Hills is shaped by proximity to MemorialCare Saddleback Medical Center on Health Center Drive. Older Alicia and Moulton corridor centers host dental, derm, and therapy operators. Honali Plaza's power-center co-tenancy supports retail-facing health services (urgent care, med spa, optical) where parking is easy and signage reads quickly.

Population

30,740

Median HHI

$128,851

Median age

41.7

Homeownership

70%

Source: U.S. Census Bureau, American Community Survey 2020-2024 5-year estimates.

Primary retail corridors

Alicia Parkway · El Toro Road · La Paz Road · Paseo de Valencia · Moulton Parkway

Centers worth touring for medical retail space in Laguna Hills

Specific shopping centers in Laguna Hills that already carry credible co-tenancy for this use. Listed in approximate order of fit.

Honali Plaza (Laguna Hills)

24721–24781 Alicia Parkway

Anchors / key tenants: Marshalls, Dollar Tree

Power-center pocket at Alicia/I-5 with the strongest national co-tenancy in Laguna Hills. The center had an Amazon Fresh, and Amazon announced in January 2026 that it would close all of its Amazon Fresh stores, so confirm what now occupies that box. New food tenants include Mendocino Farms, Dave's Hot Chicken, Five Guys, and Dutch Bros. The premium destination for fast-casual and beauty/wellness in the city.

Laguna Hills Plaza

24801–24881 Alicia Parkway

Anchors / key tenants: national grocery store (opening)

Repositioning around a national grocery anchor; suits service retail and food positioned around the future grocery footfall.

Medical Retail Space operators already in Laguna Hills

Existing operators are the most honest comp for whether a use can support Laguna Hills rents. These are publicly visible medical retail space businesses currently trading in the market.

MemorialCare Saddleback Medical Center
24451 Health Center Drive, Laguna Hills, CA 92653
Hospital campus that anchors medical demand in the city; outpatient and specialty offices tend to locate nearby.

What to diligence before LOI

01
ADA path from accessible parking: Older Alicia/Moulton suites often have stepped or tight entries that need landlord capital to fix.
02
Plumbing and exam-room buildout cost in 1980s shells.
03
Adjacency to Saddleback Medical Center pulls referral patients but also brings restrictive use covenants in some centers.
04
After-hours access and signage that reads 'medical' without being clinical from the storefront.

Sources

Zoning, licensing, and demographic figures on this page come from the public records below. Codes and licenses change, so confirm with the city and the licensing agency before you sign.

MemorialCare, Saddleback Medical Center location page

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