Lake Forest / South Orange County
Medical Retail Space in Lake Forest
Portola Parkway and Towne Centre Drive in Foothill Ranch are where lab and urgent care users already sit: Quest (26672 Portola), Labcorp (26700 Towne Centre) and Clineva Urgent Care (29100 Portola, Suite B) all list addresses there. Providence's Mission Heritage Medical Group also says it has medical offices in Foothill Ranch and Lake Forest. Elsewhere, a dental, optometry or physical therapy office would be looking at CVS on Lake Forest Drive or the grocery and service strip on the 23600 and 23700 blocks of El Toro Road, where Smart & Final, Ulta Beauty and Massage Envy have their own location pages. Because Lake Forest permits medical offices by right in all four main non-residential categories, the choice of suite is mostly a question of parking, plumbing and landlord use clauses rather than zoning.
Population
86,281
Median HHI
$135,175
Median age
40.2
Homeownership
70.5%
Source: U.S. Census Bureau, American Community Survey 2020-2024 5-year estimates.
Primary retail corridors
El Toro Road · Rockfield Boulevard · Bake Parkway · Trabuco Road · Lake Forest Drive
Medical Retail Space operators already in Lake Forest
Existing operators are the most honest comp for whether a use can support Lake Forest rents. These are publicly visible medical retail space businesses currently trading in the market.
Clineva Urgent Care Lake Forest
29100 Portola Parkway, Suite B, Lake Forest, CA 92630
Walk-in urgent care in a numbered suite, with X-ray, lab testing, physicals, occupational health and point-of-care ultrasound listed on the operator's own clinic page. One of six Clineva clinics in Orange County.
Quest Diagnostics
26672 Portola Parkway, Lake Forest, CA 92610
Patient service center for lab draws, the only Quest location on its Lake Forest locator page. In the Foothill Ranch ZIP code.
Labcorp
26700 Towne Centre Drive, Foothill Ranch, CA 92610
Patient service center listed on Labcorp's Foothill Ranch locator page, in the same 92610 ZIP code as the Quest site.
CVS Pharmacy
21761 Lake Forest Drive, Lake Forest, CA 92630
The one CVS store CVS's locator shows in Lake Forest, with pharmacy and immunization services. The store listing did not show a MinuteClinic.
What to diligence before LOI
01
Zoning: the Land Use Matrix in Section 9.72.090 permits Medical Office in the C, I, PA and UA categories. Section 9.04.030 defines it as space for health care professionals providing outpatient services, including medical doctors, walk-in clinics, dentists and chiropractors, with diagnosis, X-ray, laboratory or surgical facilities allowed on site but no overnight care. An Emergency Health Service Facility, which the code treats as a hospital, needs a use permit in C, PA and UA and is prohibited in I.
02
Parking: Section 9.168.070 parks medical and dental clinics or offices at 1 space per 250 sq ft, the same as general office and lower than the 1 per 200 sq ft required for general retail. On paper a clinic needs fewer spaces than the store it replaces, but a busy urgent care or dental practice can outrun that ratio, so ask the landlord for actual peak-hour counts and any parking or use limits in the center's CC&Rs.
03
Pharmacy and retail medical: the matrix permits Pharmacy only in C and UA, and Retail Business is accessory only in I (capped at 15% of floor area by footnote 1). A clinic in an industrial or business park building can sell some products, but a retail pharmacy counter needs a C or UA site.
04
Occupancy change: the 2025 California Building Code lists ambulatory care facilities, outpatient clinics and physician and dentist offices as Group B (Section 304.1), with ambulatory care facilities also subject to Section 422 (Section 304.3), while retail stores are Group M (Section 309.1). Moving a clinic into a former store is a change of occupancy that the Lake Forest Building and Safety Division, (949) 461-3470, will review.
05
Path of travel and restrooms: Section 11B-202.4 of the 2025 California Building Code requires an accessible path of travel to the altered area, including the primary entrance and the toilet facilities serving it. Under Exception 8, projects at or below the valuation threshold cap that spending at 20% of the adjusted construction cost. Settle in the lease who pays for restroom, entrance and parking-stall upgrades.
06
Foothill Ranch parcels: the Foothill Ranch Planned Community text (PC 8) sends Commercial land uses to matrix column C but sends parking to the PC's own Section XIX. For a Towne Centre Drive or Portola Parkway suite, confirm with Planning at (949) 461-3535 which parking table applies before you count on the 1 per 250 medical ratio.
Sources
Zoning, licensing, and demographic figures on this page come from the public records below. Codes and licenses change, so confirm with the city and the licensing agency before you sign.
- Lake Forest Municipal Code Section 9.72.090, Land use matrix (Zoneomics mirror, amendments shown through Ord. 378, 6/17/2025)
- Lake Forest Municipal Code Section 9.04.030, Definitions (Zoneomics mirror)
- Lake Forest Municipal Code Section 9.168.070, Off-street parking requirements (Zoneomics mirror, amendments shown through Ord. 374, 2/4/2025)
- City of Lake Forest, Guide to Using the Non-Residential Land Use Matrix (PDF)
- City of Lake Forest, Foothill Ranch Planned Community text (PC 8, PDF)
- City of Lake Forest, Regulations & Permits
- 2025 California Building Code, Chapter 3, Sections 304.1, 304.3 and 309.1 (UpCodes)
- 2025 California Building Code, Chapter 11B, Section 11B-202.4 (UpCodes)
- Clineva Urgent Care, Lake Forest clinic page
- Clineva Urgent Care, all locations
- Quest Diagnostics, 26672 Portola Pkwy, Lake Forest
- Labcorp, Foothill Ranch locations
- CVS Pharmacy, Lake Forest store locator
- Providence, Mission Heritage Medical Group
- Smart & Final store data on smartandfinal.com (store list embedded in the site's stores page)
- Ulta Beauty, Lake Forest store 467
- Massage Envy, Lake Forest locations
- U.S. Census Bureau, ACS 2020-2024 5-year estimates, table DP05, Lake Forest city, California
- U.S. Census Bureau, ACS 2020-2024 5-year estimates, table DP03, Lake Forest city, California
- Cushman & Wakefield MarketBeat, Orange County Retail, Q2 2026 (PDF)