Yorba Linda / North Orange County
Medical users in Yorba Linda cluster in two places on Yorba Linda Boulevard. The west end, from about 16600 to 16700 E. Yorba Linda Blvd near Rose Drive, has UCI Health's outpatient center, a MemorialCare-listed physical therapy clinic and, until May 2026, a UCI orthopaedic site, with Labcorp nearby on Rose Drive. The second is UCI Health's larger imaging and specialty center at 18637 Yorba Linda Boulevard, east of the Town Center corner at Imperial Highway. The city's commercial table permits medical and dental clinics under 10,000 sq ft by right in all three commercial zones, so smaller practices can go into neighborhood centers without a hearing.
Population
67,170
Median HHI
$157,582
Median age
44.9
Homeownership
83%
Source: U.S. Census Bureau, American Community Survey 2020-2024 5-year estimates.
Primary retail corridors
Yorba Linda Boulevard · Imperial Highway · Savi Ranch Parkway · La Palma Avenue · Lakeview Avenue
Specific shopping centers in Yorba Linda that already carry credible co-tenancy for this use. Listed in approximate order of fit.
Yorba Linda Boulevard at Imperial Highway
Anchors / key tenants: Bristol Farms, Edwards Cinemas
Size: 125,000 SF
Upscale 125,000 SF entertainment, restaurant, and service center on the city's most prominent corner. Bristol Farms-anchored specialty grocery serves the affluent Yorba Linda household ($152k HHI, 83% homeownership). Open-space commons drives lingering visit pattern.
22999 Savi Ranch Parkway
Anchors / key tenants: Costco, Sprouts Farmers Market, Best Buy, Michaels, Ashley HomeStore
Size: 160,773 SF
Yorba Linda's commercial hub — Costco/Sprouts-anchored regional center with home, electronics, and craft category co-tenancy. Casual dining (Keno's, Moreno's).
Existing operators are the most honest comp for whether a use can support Yorba Linda rents. These are publicly visible medical retail space businesses currently trading in the market.
UCI Health, Yorba Linda
18637 Yorba Linda Boulevard, Yorba Linda, CA 92886
Multi-specialty outpatient center with cancer care, cardiology, dermatology, orthopedics, lab, an infusion center and imaging (3-Tesla MRI, 3D mammography, ultrasound, walk-in X-ray), per UCI Health's own page. On Yorba Linda Boulevard east of Imperial Highway, near Yorba Linda Town Center.
UCI Health, Yorba Linda Outpatient Center: Rose Drive
16671 E. Yorba Linda Boulevard, Suites 100, 200 and 210, Yorba Linda, CA 92886
Primary care (Suite 100), gastroenterology (Suite 200) and women's health and general surgery (Suite 210), per UCI Health's page. UCI Health's nearby orthopaedic site at 16611 E. Yorba Linda Blvd is marked permanently closed as of May 1, 2026.
California Rehabilitation & Sports Therapy, Yorba Linda
16615 Yorba Linda Boulevard, Yorba Linda, CA 92886
Physical therapy and sports rehab in a 2,500 sq ft center with private treatment rooms, per its MemorialCare location page. A useful size reference for a PT suite.
Labcorp Patient Service Center
4300 Rose Drive, Suite T, Yorba Linda, CA 92886
Routine testing and screenings with walk-ins welcome, per Labcorp's location page.
01
Size threshold: Table 18.12-1 (Section 18.12.050) permits a medical/dental clinic of less than 10,000 sq ft by right in C-O, C-N and C-G. A clinic of 10,000 sq ft or more located in a center with shared parking needs a CUP in all three zones, heard by the Planning Commission (Section 18.36.230). Keep a first lease under 10,000 sq ft unless the timeline allows a hearing. Sample laboratories are permitted in all three zones.
02
Parking: Table 18.22-1 parks medical, dental and other health offices at 1 space per 200 sq ft, the same rate as general retail, and a shopping center of 25,000 sq ft or more parks at 5 per 1,000 for mixed occupancies (18.22.030.A.5). So a retail-to-medical change in the same suite should not raise the count, and Section 18.22.020.C adds no parking where a change raises the requirement by less than 10%. Get Planning to confirm the count for your suite.
03
Second-generation space: UCI Health lists its orthopaedic site at 16611 E. Yorba Linda Blvd as permanently closed as of May 1, 2026. Ask the owner whether that space is available and which medical improvements remain before pricing a new build-out on that block.
04
Imaging and dental X-ray: the California Department of Public Health's Radiologic Health Branch says 17 CCR 30108 requires registering any X-ray machine within 30 days of acquiring it, and registration runs two years. Ask the Yorba Linda Building Division early what shielding, plumbing and accessible restroom documentation it will need on the plans.
05
Two-story and residential edges: where a commercial lot abuts a residential zone, Section 18.12.070.B bars a two-story building without a Planning Commission CUP and Section 18.12.070.A requires a 50-foot setback. This matters for ground-up medical office on Yorba Linda Boulevard lots that back onto homes.
06
Specific plan and PD sites: if the parcel is inside the Yorba Linda Town Center Specific Plan or one of the PD-1 to PD-30 zones the city maps, its own use list may govern instead of Table 18.12-1. Check the governing document on Map Yorba Linda before relying on the by-right clinic rule.
Zoning, licensing, and demographic figures on this page come from the public records below. Codes and licenses change, so confirm with the city and the licensing agency before you sign.